Evren U. Azeloglu, Ph.D.

Evren U Azeloglu

Associate Professor
Icahn School of Medicine at Mount Sinai
Department of Medicine, Nephrology
One Gustave L. Levy Place, Box 1243
New York, NY 10029

Tel: (212) 241-8519
Fax: (212) 831-0114

 

Investigator

Dr. Azeloglu is an Associate Professor of Medicine and Pharmacological Sciences at Icahn School of Medicine at Mount Sinai. His research interests focus on systems bioengineering, with the specific goal of understanding cellular decision-making capabilities related to biomechanical and electrochemical signal processing. Originally trained as a mechanical engineer, he received his PhD in biomedical engineering from Columbia University and completed his postdoctoral training in systems biology at Mount Sinai. His group employs multiscale experimental and computational techniques as well as microfabrication and tissue engineering methods to study cell signaling, cytoskeletal biomechanics, tissue function and regeneration using renal and cardiovascular model systems. He also uses his expertise in multi-platform omics technologies and network analysis for identification of key information processing hubs and regulatory motifs that can be used as therapeutic targets in drug development for complex diseases such as diabetic nephropathy and heart failure. He enjoys exercise and outdoorsy activities of all kinds and loves New York City.

Maria Paola Santini, Ph.D.

Maria Paola Santini, Ph.D

Assistant Professor
Icahn School of Medicine at Mount Sinai
Department of Medicine, Nephrology
One Gustave L. Levy Place, Box 1243
New York, NY 10029

 

Investigator

Dr. Santini is an Assistant Professor of Medicine at Icahn School of Medicine at Mount Sinai. Her research interest focuses on regenerative medicine, with the specific goal of understanding the mechanisms regulating fibro-adipogenic response in multiorgan studies. Dr. Santini was trained as a molecular and cellular biologist, she received her PhD in molecular biology from Heidelberg University and the European Biology Laboratory, Heidelberg, Germany, and completed her postdoctoral training in regenerative medicine at Imperial College London, London, UK. Her research uses transgenic technologies as well as in vivo and ex vivo cardiac and kidney disease models to investigate cell signaling, tissue cross-talk, revascularization, and regeneration. Methodological analyses of murine and human samples are performed using cell lineage microsopy analyses and multi-platform omics technologies to identify key drivers of cardiac and renal diseases. Important targets for complex disease analyses include the Insulin-like Growth Factor-1 as a therapeutic and pharmacological agent, Notch downstream molecules and Platelet-Derived Growth Factor Receptor alpha as specific modulators of heart and kidney failure. She enjoys traveling and meeting people from different cultures. Her motto is ‘Travel makes one modest. You see what a tiny place you occupy in the world, Gustave Flaubert’